To prevent deafness, parents should pay attention to these five kinds of drugs

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In China, the number of people with hearing disability ranks first among the five disabled people. The results of the sixth national census show that the number of deaf children under 7 years old is more than 800000, of which 300000 are caused by irrational use of drugs, accounting for 30% – 40% of the total deaf children. The abuse and misuse of ototoxic drugs are the main causes of children’s acquired deafness.

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Pan Yan, director of the Department of Otolaryngology, Affiliated Hospital of Anhui Traditional Chinese medicine, said that compared with adults, children are more likely to have drug-induced deafness, mainly for two reasons. Children’s immunity is not perfect, and their resistance to viruses and bacteria is weak. They are more likely to suffer from colds, fever and other infectious diseases than adults. It is easy to cause otitis media, and improper treatment will affect children’s hearing. Children’s inner ear and auditory nerve are in the growth and development period, and they are more sensitive to ototoxic drugs. Newborn and infant are more likely to suffer from drug-induced deafness due to their poor renal function and poor drug excretion ability.

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At present, more than 100 kinds of ototoxic drugs have been found, which can be divided into the following categories:

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1. Antibiotics

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Ototoxic antibiotics can be divided into aminoglycosides, macrolides, amide alcohols, tetracyclines and other antibiotics. Among them, aminoglycoside antibiotics can cause serious and irreversible ototoxicity, which is forbidden for children under 6 years old, pregnant women and 65 year old people. Other common antibiotics harmful to children’s hearing, including erythromycin in macrolides, vancomycin hydrochloride in other classes, etc.

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2. Antipyretic, analgesic and anti-inflammatory drugs

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Including aspirin, phenacetin, ibuprofen, etc., excessive use can cause poisoning, but also lead to mild to moderate bilateral symmetrical hearing loss.

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3. Antimalarial drugs

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Antimalarial drugs such as quinine, chloroquine phosphate and pyrimethamine are easy to cause ototoxicity to pregnant women and infants.

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4. Antineoplastic drugs

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Including cisplatin, vincristine, nitrogen mustard, methotrexate, bleomycin, etc., improper use can damage inner ear hair cells, resulting in irreversible deafness.

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5. Diuretics

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Clinical commonly used are bumetanide, furosemide, diuretic acid and so on, long-term intravenous administration, and too fast can cause tinnitus, deafness.

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The parents are reminded that the drugs to be used by children must be strictly in accordance with the doctor’s instructions. If you have to use the above drugs, you should determine the dosage according to the weight of the child and the safe dosage of the drugs, through accurate calculation and according to the doctor’s order. Observe the children’s reaction closely during the course of taking medicine. Once the children’s voice response ability is found to be poor, stop taking medicine immediately and see a doctor in time.

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